P-value avg_log2FC pct.1 pct.2 adjusted P-value cluster gene 1.03E-232 3.904619742 0.837 0.049 2.93E-228 HCM NPPA 1.08E-227 3.340730185 0.983 0.726 3.09E-223 HCM TPM3 7.89E-223 3.692703537 0.921 0.341 2.25E-218 HCM NPPB 1.83E-187 1.146796454 0.999 0.985 5.23E-183 HCM FBXO32 2.06E-185 2.25217321 0.831 0.193 5.89E-181 HCM LUM 2.20E-172 2.62718696 0.856 0.299 6.28E-168 HCM ACE2 1.72E-171 1.526633775 0.987 0.942 4.92E-167 HCM TNNT1 6.58E-168 1.506734002 0.979 0.872 1.88E-163 HCM FILIP1L 3.31E-165 2.051089163 0.946 0.503 9.46E-161 HCM RTN4 1.34E-164 1.081590215 0.999 0.993 3.84E-160 HCM SYNPO2L 1.94E-162 1.18275315 0.992 0.959 5.54E-158 HCM PDE1C 7.07E-161 1.964121891 0.949 0.662 2.02E-156 HCM SOX4 3.82E-148 1.649877108 0.961 0.721 1.09E-143 HCM HLA-A 1.29E-147 1.499674352 0.949 0.738 3.69E-143 HCM KIF13A 7.52E-139 1.944061323 0.706 0.139 2.15E-134 HCM FN1 6.95E-138 1.044905314 0.991 0.985 1.98E-133 HCM GJA1 3.33E-132 1.190711412 0.98 0.929 9.52E-128 HCM EXOC6B 9.20E-132 1.885150498 0.7 0.151 2.63E-127 HCM COL1A2 2.38E-131 1.269015419 0.981 0.895 6.79E-127 HCM CRIM1 5.34E-131 1.41993033 0.959 0.756 1.52E-126 HCM PLK2 4.93E-129 1.4374367 0.944 0.739 1.41E-124 HCM MYOCD 6.20E-126 1.093717638 0.997 0.982 1.77E-121 HCM NMRK2 1.60E-125 1.826617993 0.834 0.394 4.57E-121 HCM PLCE1 4.59E-124 1.68693623 0.889 0.538 1.31E-119 HCM ACTN1 3.16E-118 1.645514568 0.552 0.042 9.02E-114 HCM RP11-43F13.3 3.56E-116 1.225010962 0.966 0.86 1.02E-111 HCM LTBP1 1.01E-114 1.521736573 0.915 0.598 2.88E-110 HCM DCN 2.70E-114 1.504661927 0.63 0.117 7.70E-110 HCM THBS4 2.78E-113 1.577064867 0.909 0.624 7.93E-109 HCM FNBP4 1.20E-112 1.345492673 0.981 0.927 3.43E-108 HCM NES 1.09E-111 1.412437442 0.953 0.866 3.11E-107 HCM PROS1 6.52E-111 1.10035521 0.964 0.904 1.86E-106 HCM INPP4B 3.58E-110 1.194227209 0.954 0.838 1.02E-105 HCM CCND1 1.05E-106 1.50166265 0.921 0.689 3.01E-102 HCM SLC27A6 2.32E-106 1.887159088 0.622 0.139 6.62E-102 HCM CCDC80 7.29E-106 1.21739249 0.942 0.777 2.08E-101 HCM UACA 1.28E-103 1.097146569 0.962 0.828 3.66E-99 HCM NRP1 2.36E-101 1.183031388 0.927 0.758 6.75E-97 HCM YPEL2 3.94E-101 1.763670383 0.675 0.218 1.12E-96 HCM TIMP1 4.04E-100 1.28070563 0.927 0.743 1.15E-95 HCM SEMA5A 9.77E-96 1.218245989 0.908 0.691 2.79E-91 HCM XPO4 1.50E-93 1.27558569 0.861 0.533 4.29E-89 HCM FBXO9 1.58E-93 1.363454196 0.412 0.005 4.50E-89 HCM ZFP57 4.12E-93 1.563556936 0.731 0.311 1.18E-88 HCM IGFBP2 4.23E-91 1.372239182 0.851 0.547 1.21E-86 HCM MYOF 2.91E-90 1.329863525 0.894 0.619 8.29E-86 HCM MGP 1.73E-89 1.711651367 0.844 0.544 4.95E-85 HCM THBS1 2.25E-89 1.227629483 0.938 0.818 6.43E-85 HCM NPR3 2.76E-89 1.107006122 0.95 0.806 7.87E-85 HCM PROX1 6.46E-89 1.349629314 0.828 0.513 1.84E-84 HCM RUNX1T1 1.72E-88 1.35253049 0.496 0.068 4.92E-84 HCM COL3A1 2.57E-88 1.480068932 0.929 0.684 7.33E-84 HCM RGS5 6.08E-88 1.850585296 0.83 0.488 1.74E-83 HCM GNG11 8.80E-88 1.196935419 0.902 0.675 2.51E-83 HCM CHRM2 4.32E-87 1.071312651 0.923 0.743 1.23E-82 HCM RBM3 2.61E-86 1.386641233 0.769 0.367 7.46E-82 HCM VIM 2.71E-86 1.169350595 0.94 0.787 7.74E-82 HCM GPC1 7.12E-86 1.269259475 0.901 0.713 2.03E-81 HCM F3 1.27E-85 1.050686279 0.942 0.809 3.63E-81 HCM MAP4K4 8.66E-85 1.085511318 0.953 0.85 2.47E-80 HCM PTRF 3.57E-84 1.003471773 0.943 0.846 1.02E-79 HCM FAM198B 1.30E-83 1.167993412 0.905 0.679 3.72E-79 HCM NAV1 5.44E-83 1.354834711 0.642 0.226 1.55E-78 HCM PIK3IP1 9.35E-83 1.416292973 0.771 0.419 2.67E-78 HCM PHLDA1 2.27E-82 1.374128283 0.499 0.087 6.48E-78 HCM ASPN 7.83E-82 1.447907285 0.771 0.385 2.24E-77 HCM SPARC 1.16E-81 1.290361936 0.744 0.363 3.31E-77 HCM MGLL 9.43E-80 1.447869709 0.597 0.175 2.69E-75 HCM PCLO 4.42E-79 1.232380128 0.858 0.595 1.26E-74 HCM NIN 1.64E-78 1.278939197 0.549 0.149 4.68E-74 HCM RASL11B 2.31E-78 1.281725825 0.878 0.645 6.59E-74 HCM CASQ1 1.92E-77 1.112401857 0.953 0.804 5.48E-73 HCM G0S2 2.47E-77 1.359329316 0.446 0.062 7.04E-73 HCM DIO2 1.59E-76 1.172908914 0.888 0.59 4.54E-72 HCM HLA-B 2.02E-76 1.73502448 0.585 0.202 5.76E-72 HCM MAP2 2.55E-76 1.244298397 0.453 0.066 7.28E-72 HCM BGN 6.54E-76 1.82700308 0.439 0.058 1.87E-71 HCM CA3 4.70E-75 1.017711172 0.903 0.707 1.34E-70 HCM TINAGL1 6.60E-74 1.221225206 0.784 0.483 1.89E-69 HCM GOLGA8B 3.69E-73 1.168926846 0.89 0.679 1.05E-68 HCM TMEM176B 2.60E-72 1.092448838 0.919 0.812 7.43E-68 HCM MAGI1 3.95E-72 1.274945929 0.464 0.089 1.13E-67 HCM MID1 2.25E-69 1.049461706 0.881 0.715 6.43E-65 HCM PCNXL4 4.78E-69 1.558392947 0.712 0.376 1.36E-64 HCM CENPA 1.51E-68 1.17592353 0.755 0.435 4.30E-64 HCM S1PR1 3.94E-68 1.261662073 0.509 0.134 1.12E-63 HCM UCHL1 1.28E-67 1.074410171 0.889 0.695 3.65E-63 HCM KMT2A 3.85E-67 1.160487645 0.913 0.823 1.10E-62 HCM WASL 4.69E-67 1.601220328 0.329 0.012 1.34E-62 HCM SLITRK4 5.69E-67 1.24080138 0.373 0.038 1.62E-62 HCM MAP3K7CL 2.95E-66 1.14960065 0.738 0.411 8.43E-62 HCM PACS1 5.30E-65 1.126619899 0.776 0.49 1.51E-60 HCM RBMS3 3.28E-64 1.228918795 0.728 0.417 9.36E-60 HCM CXXC5 5.05E-64 1.083370787 0.885 0.667 1.44E-59 HCM TM7SF2 1.99E-63 1.071611848 0.624 0.256 5.69E-59 HCM IRX6 4.05E-63 1.001215569 0.837 0.614 1.16E-58 HCM HDAC9 7.40E-63 1.079987754 0.882 0.729 2.11E-58 HCM PWAR6 2.94E-61 1.046580867 0.491 0.135 8.39E-57 HCM COL15A1 3.47E-61 1.30889836 0.757 0.496 9.91E-57 HCM HSPA2 7.38E-60 1.095043681 0.369 0.052 2.11E-55 HCM AEBP1 1.76E-59 1.015792919 0.857 0.669 5.03E-55 HCM PDLIM7 7.56E-59 1.077396208 0.459 0.116 2.16E-54 HCM COL1A1 9.84E-59 1.111588524 0.661 0.316 2.81E-54 HCM CXCL12 1.03E-58 1.039277766 0.835 0.621 2.93E-54 HCM ZMYND8 4.18E-58 1.019711823 0.773 0.475 1.19E-53 HCM FAM13B 5.91E-58 1.183369498 0.389 0.07 1.69E-53 HCM PTGER3 2.18E-56 1.078840595 0.345 0.048 6.23E-52 HCM DPYSL3 2.01E-55 1.109341801 0.667 0.359 5.75E-51 HCM CADPS 2.41E-55 1.106072341 0.566 0.224 6.89E-51 HCM KCNK6 1.48E-54 1.216891172 0.545 0.214 4.24E-50 HCM EPHA4 2.08E-54 1.039953374 0.852 0.667 5.95E-50 HCM TRPM7 1.66E-53 1.010749005 0.813 0.554 4.73E-49 HCM TIMP2 1.89E-53 1.650232248 0.68 0.353 5.39E-49 HCM NEB 2.45E-53 1.010617331 0.398 0.087 6.98E-49 HCM PTN 4.51E-52 1.151798702 0.444 0.132 1.29E-47 HCM TTLL7 8.17E-52 1.08576881 0.472 0.157 2.33E-47 HCM FARP1 3.33E-51 1.12200787 0.271 0.014 9.52E-47 HCM IGSF1 4.23E-51 1.085753286 0.797 0.563 1.21E-46 HCM S100A11 8.00E-50 1.054364115 0.475 0.166 2.28E-45 HCM UCP2 1.08E-49 1.043437097 0.679 0.392 3.09E-45 HCM TCF4 1.24E-49 1.041108916 0.61 0.296 3.55E-45 HCM TBX3 2.68E-49 1.054122992 0.516 0.198 7.64E-45 HCM TGFB2 5.92E-49 1.011159803 0.769 0.541 1.69E-44 HCM DPF3 1.70E-48 1.044758508 0.952 0.881 4.85E-44 HCM APOA1 2.34E-48 1.01577664 0.606 0.294 6.67E-44 HCM TMEM176A 4.79E-48 1.029045023 0.467 0.154 1.37E-43 HCM ARFGEF3 1.22E-46 1.051174242 0.61 0.322 3.49E-42 HCM ANKRD33B 3.52E-45 1.016684536 0.642 0.36 1.01E-40 HCM BCL2 6.55E-42 1.056598932 0.68 0.395 1.87E-37 HCM BEX1 6.54E-38 1.074252504 0.513 0.251 1.87E-33 HCM CLIC6 2.56E-288 3.388790809 0.974 0.238 7.31E-284 NC LINC01170 1.48E-264 2.459554692 0.999 0.891 4.23E-260 NC MT1X 5.32E-240 2.409595156 0.977 0.417 1.52E-235 NC C10orf11 1.65E-238 1.438869992 0.999 0.967 4.71E-234 NC MT1E 6.53E-234 1.34120909 1 0.994 1.86E-229 NC MT2A 1.17E-232 1.978436731 0.739 0.043 3.33E-228 NC C21orf33 1.14E-216 1.766388248 0.995 0.857 3.25E-212 NC RP11-245G13.2 3.15E-193 2.028868694 0.98 0.595 8.99E-189 NC LINC00844 1.23E-191 2.320640373 0.958 0.455 3.51E-187 NC AREG 2.38E-185 1.347567177 0.999 0.953 6.80E-181 NC OTUD1 6.91E-178 1.376767185 1 0.815 1.97E-173 NC FGF12 2.36E-177 1.899761125 0.635 0.047 6.74E-173 NC FABP2 3.20E-175 1.229655621 1 0.966 9.13E-171 NC BTG2 1.78E-173 1.458598376 0.934 0.675 5.08E-169 NC ATP5EP2 2.16E-161 1.145459691 0.994 0.939 6.18E-157 NC PEBP4 5.30E-159 1.10147218 0.999 0.972 1.51E-154 NC DUSP1 1.48E-147 1.336644394 0.632 0.081 4.23E-143 NC PCDH8 1.94E-147 1.064728349 1 0.983 5.55E-143 NC ZFP36 2.12E-146 1.896342066 0.919 0.598 6.04E-142 NC PACRG 7.41E-145 1.026072471 0.995 0.949 2.11E-140 NC EMC3 1.31E-141 1.047434987 0.985 0.913 3.73E-137 NC PRR34-AS1 2.07E-137 1.701057445 0.8 0.278 5.90E-133 NC DKFZp779M0652 1.39E-133 1.378686775 0.948 0.522 3.95E-129 NC CORIN 6.09E-133 1.203486867 0.983 0.79 1.74E-128 NC LINC00881 4.89E-130 1.198461844 0.977 0.804 1.40E-125 NC RP11-140K17.3 1.19E-127 1.015455953 0.988 0.911 3.39E-123 NC TPRKB 1.18E-125 1.751987472 0.68 0.177 3.38E-121 NC RASD1 2.81E-118 1.552536429 0.665 0.179 8.02E-114 NC AC005592.1 2.67E-105 1.323343671 0.886 0.498 7.63E-101 NC CEBPD 3.85E-104 1.652053483 0.835 0.438 1.10E-99 NC RP11-161D15.1 7.97E-103 1.443370986 0.621 0.152 2.28E-98 NC RP11-121C2.3 1.12E-101 1.010458603 0.531 0.096 3.20E-97 NC FOXP1-AS1 1.33E-99 1.527709789 0.705 0.276 3.79E-95 NC KCNIP2 6.24E-98 1.052546499 0.959 0.738 1.78E-93 NC CDKN1A 4.81E-91 1.404297795 0.752 0.343 1.37E-86 NC RIIAD1 5.52E-85 1.139351697 0.496 0.111 1.58E-80 NC CA14 6.22E-84 1.188875833 0.701 0.275 1.78E-79 NC MT3 1.83E-83 1.172351178 0.787 0.415 5.22E-79 NC DUSP5 1.38E-79 1.10295808 0.877 0.592 3.93E-75 NC TKTL1 8.52E-77 1.12176945 0.614 0.206 2.43E-72 NC TNFAIP8 2.09E-76 1.734857002 0.759 0.418 5.97E-72 NC CDCA2 2.41E-74 1.190936022 0.852 0.514 6.89E-70 NC MYBPC1 1.10E-72 1.085313755 0.669 0.277 3.14E-68 NC DUSP2 1.68E-71 1.110461185 0.531 0.148 4.79E-67 NC SCGB1D2 2.27E-71 1.108060152 0.41 0.076 6.48E-67 NC PDE4B 5.01E-71 1.102512872 0.492 0.137 1.43E-66 NC FAM46B 4.81E-70 1.031075164 0.466 0.121 1.37E-65 NC TUBA3D 3.47E-65 1.065270996 0.675 0.323 9.90E-61 NC ROPN1B 2.15E-64 1.077215003 0.389 0.08 6.13E-60 NC TDRD9 6.73E-62 1.00520415 0.588 0.237 1.92E-57 NC SRGAP3-AS4 1.99E-61 1.098422831 0.539 0.192 5.68E-57 NC APOLD1 7.64E-60 1.012957332 0.651 0.317 2.18E-55 NC TRIB1 1.19E-58 1.11349104 0.525 0.189 3.38E-54 NC NSG1 2.97E-56 1.068133404 0.523 0.19 8.48E-52 NC PATL2 2.84E-54 1.008043101 0.622 0.297 8.12E-50 NC RP4-665J23.1 4.86E-54 1.148248324 0.53 0.217 1.39E-49 NC CCDC146 2.45E-50 1.000633142 0.692 0.422 7.00E-46 NC RP11-539L10.3 8.22E-50 1.076036603 0.579 0.259 2.35E-45 NC HOPX 2.49E-44 1.118597302 0.267 0.045 7.12E-40 NC MT1G 2.73E-44 1.040411261 0.731 0.486 7.80E-40 NC TMEM107 1.69E-10 1.447284311 0.605 0.485 4.82E-06 NC SLC35A3